p140Cap Controls Female Fertility in Mice Acting via Glutamatergic Afference on Hypothalamic Gonadotropin-Releasing Hormone Neurons

p140Cap, encoded by the gene SRCIN1 (SRC kinase signaling inhibitor 1), is an adaptor/scaffold protein highly expressed in the mouse brain, participating in several pre- and post-synaptic mechanisms.p140Cap knock-out (KO) female mice show severe hypofertility, delayed puberty onset, Gaming Desk altered estrus cycle, reduced ovulation, and defective

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Multidisciplinary management of thoracic aortic injury with hemodynamically unstable pelvic fracture in the elderly

Abstract Blunt thoracic aortic injury (BTAI) is a critical clinical emergency often presenting as severe trauma.The early diagnosis and treatment of BTAI pose significant challenges in its management, especially when patients experience early-stage hemodynamic instability.Presently, in the context of multiple traumas, there is an absence of clearly

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